Aging has been a subject of curiosity and much deliberation since ancient times. Like ticking of time the process of aging is an unstoppable phenomenon. Over the past few decades the theory of aging and disease has come under the scanner of the gerontologist and genetic scientists alike. With wide–ranging experimental molecular and genetic research on aging, the concept of a singular longevity gene has lost ground with time. What seems to be evident and palatable is that manifold factors through innumerable conduits influence the process of aging and determine longevity of any species. The gerontologists have had a daunting task to understand the science of aging, trying their very bests to unlock the peculiar characteristics of factors determining longevity, as to why some species differ in their longevity from others and why within the same species some humans live longer than others.