MANUAL OF LABORATORY ANIMAL RESEARCH

by Dr. R. Selvaraj
₹ 300
ISBN Number : 978 - 1- 73039 - 349 - 5

Dr. R. Selvaraj

Dr. R. Selvaraj is an Associate Professor / Scientist In-charge of CPCSEA approved Centre for Laboratory Animal Technology and Research, Sathyabama University, Chennai, India with eighteen years of teaching and research experience. He earned his B.Sc., M.Sc., M.Phil., & Ph.D..,l from Bharathidasan University, Tiruchirappalli, Tamil Nadu, India. His research areas include Rat Pheromone Biochemistry and Reproductive behavior of rodents. He has published more than forty research articles in peer-reviewed journals. He has delivered several invited lectures in National level conferences. He has organized more than fifteen workshops / training programmes on lab animal research and attended 45 more National and International Conferences and Training Programmes. He is a life member of Lab Animal Scientist Association (LASA), India and Journal of the Society for Biology and Biotechnology and served as a member in various committees such as Institutional Animal Ethics Committee, Institutional Bio-safety Committee, Institutional Human Ethics Committee, Ph.D Advisory Committee, Scientific Review Board, Ph.D. Thesis evaluation Committee etc., . He has been serving as a Reviewer to some National and International Journals.


Read more...


Book Overview

Laboratory animal research has come to stay in this 21st century in spite of much opposition as the sheet attach for â€the alleviation of pain and suffering for humankind and animalsâ€. Animals play a significant role in man′s life not only as a source for survival but also for human advancement. Through the discovery of the first wheel, human evolution found rapid strides in the domestication of animals and its vital usage improving not only man′s logistics but also the development of man–animal relationship. Experiments involving animals will be eventually lead to the protection and improvement of the health and welfare of both humans and animals. Toxicity studies especially those performed in rodents and beagle dogs are the necessary links between the preclinical phase and clinical development of the drug molecule. No new drug can be commenced in clinical practice or even for the matters into clinical research unless in passes the succession of toxicity tests in animals. Human biology is very much similar to that of many other animals. That is why; results from animal experiments apply to people. Most laboratory animals have the same set of organs – heart, lungs, liver, and so on which work in the same way as they do in humane. There are seven major areas of medicine and biology where animals for experiments need to be used. For the basic science, medical students as well as research scholars, the need of the hour is good exposure to knowledge of laboratory animals and experimentation. All life / medical sciences include a basic knowledge of laboratory animals without which it cannot progress. In the pharmaceutical industry the preclinical trials are essential in the new development of drug molecules for which lab animal experiment is essential. Tree of Life: Introduction 1 9 Any animals which are used for experimental purpose should be considered as laboratory animals. However, in normal sense, animals like mouse, rat, hamster, guinea pig, rabbit and restrictedly dog and monkeys are considered as laboratory animals. Animals like rat and mouse had better adaptability by their nature as omnivores in habit, healthy physical constitution, but small body size, prolific breeding and easily became domestic confinement could be the reasons for them to be domesticated with human environment. These animals were naturally–dominating in biological research. But subsequently guinea pigs from North America were introduced in experimental medical research as they are very sensitive to a number of human pathogens.